Drug Delivery

The logic of synthetic biology: turning cells into computers

Matthew R. Bennett Rice University
For years scientists have been studying E. coli as historians would an ancient tome. Biologists, biochemists, and geneticists have dissected, poked, and prodded E. coli until it gave up its secrets: the basic principles of cellular life. Synthetic biologists, on the other hand, look at E. coli and think to themselves: “let’s make a computer”.
9 April 2017

Ebola: 38 years, 25 outbreaks

Michael Edelstein & David Heymann Chatham House
While forming a key component of the recent Ebola response, much debate surrounds how clinical trials testing new experimental treatments for the disease should be designed.
26 March 2015

Donated Drugs Against Neglected Tropical Diseases

Alan Fenwick Imperial College London
One in six of the world’s population live in rural areas, and suffer from poor health - especially chronic diseases caused by infection with parasitic diseases now known as ‘Neglected Tropical Diseases’ or NTDs.
1 June 2014
Research

Improving the Immunogenicity of Vaccines

E. David G. McIntosh Novartis
For maternal infections such as group B streptococcus and early infant infections such as respiratory syncytial virus infection, there is now hope for the development of successful vaccines, some based on adjuvants which are designed to boost weak immune response.
1 June 2014
Research

The Ageing Heart

Thomas Brand Imperial College London
Research based at Imperial College in the area of Popeye domain containing aims to provide a novel insight into the ageing process and potentially provide new therapeutic opportunities to help the ageing heart.
1 May 2013

How to Plan a Successful Biopharma Product Rollout

Juergen Luecke, Judith Wallenstein, Torsten Kurth & Caroline Teichmann The Boston Consulting Group
Effectively launching a new biopharma product, however, has never been more challenging. In addition to a litany of regulatory issues, companies face high stakeholder expectations, numerous market-access hurdles, and stiff competition, all of which are made more formidable by the business realities of the industry.
1 October 2012

Antibiotics in Decline

Esmita Charani Imperial College London
The majority of antibiotic use is in the community, however the impact of antibiotic resistance is felt most acutely when treating patients in healthcare settings.
1 October 2012
Copyright 2015 ANGLE Journal